GenIC Request

OMB Control Number 0920-1282 Performance Measures Project

Request for GenIC Approval (for data collection in 2026, 2027, 2028)

Date: 07/02/2025

CIO: National Center of Emerging and Zoonotic and Infectious Diseases

PROJECT TITLE: Performance Measures Reporting for Epidemiology and Laboratory Capacity (ELC) Cooperative Agreement

PURPOSE AND USE OF COLLECTION: The ELC Cooperative Agreement (CoAg) is a key initiative of the CDC that enhances national efforts in the response, detection, prevention, and control of infectious diseases. This request seeks to quantify performance measure data collection activities for the ELC CoAg, as the performance measures will help assess the successes, challenges, and outcomes of the ELC funding implementation. To facilitate this, CDC has developed standard performance measures for all ELC recipients. These measures are designed to assess progress and identify areas for improvement.

NUMBER AND TITLE OF NOFO: Epidemiology and Laboratory Capacity for Prevention and Control of Emerging Infectious Diseases (ELC) CDC-RFA-CK-24-0002

NUMBER OF PARTICIPATING RECIPIENTS: 65

ESTIMATED ANNUAL FUNDING: 230,000,000

DESCRIPTION OF NOFO (check all that apply):

_X_ Funds all 50 states

_X_ Has budget higher than $10 million per year

_X_ Has significant stakeholder interest (e.g. partners, Congress)

Please elaborate:

The ELC Cooperative Agreement (CoAg), established in 1995, plays a vital role in strengthening U.S. public health infrastructure. The goal of the Epidemiology and Laboratory Capacity for Prevention and Control of Emerging Infectious Diseases (ELC) Cooperative Agreement is to provide capacity building support and technical assistance, helping to reduce morbidity and mortality caused by a wide range of infectious disease threats. The ELC provides annual funding, strategic direction, and technical assistance to state, local, and territorial jurisdictions to strengthen core capacities in epidemiology, laboratory, and health information systems (HIS) activities. In addition to strengthening core infectious disease capacities nationwide, this cooperative agreement also supports numerous specific infectious disease programs and projects. Over the previous five years, the ELC Cooperative Agreement awarded an average of

$230,000 annually in non-supplemental funding to enhance these departments' capabilities in detecting, responding to, preventing, and controlling infectious diseases.

ELC serves both as a robust response-ready program, as well as a multi-component “umbrella” funding mechanism, awarding various Congressional appropriations on behalf of several CDC programs. The cooperative agreement includes 21 distinct programs and projects; of which six are pathogen independent infectious disease programs and 15 are disease-specific projects, with each varying in funding amount and performance complexity. Without the streamlined “umbrella” CoAg structure of ELC, at least 10 stand-alone nationwide CoAgs or grants would be needed. The ELC CoAg mode of operations creates many efficiencies for both the recipients and the federal government, for example, the need for only one OMB package, instead of ten or more. This structure helps foster cross-cutting solutions to address public health needs and support a state and jurisdiction response-ready workforce. In addition to annual awards, the ELC can rapidly deploy supplemental funding to address urgent infectious disease response needs. ELC’s robust response-ready program enhances the capacity of state and local health departments in epidemiology, laboratory, leadership and management, and health information systems. Given the significant funding involved and the critical need to demonstrate how these funds prevent, detect, and control infectious disease threats in the U.S., this program garners considerable interest from state and local public health stakeholders.

PERFORMANCE METRICS USED & JUSTIFICATIONS:

Documenting impact and accountability are high priorities for the ELC, as the program is central to health departments' capacity to prevent, detect and respond to infectious diseases, nationwide. Process and outcome performance measures are collected on CoAg activities to monitor the impact of ELC funding and document progress toward strengthening infectious disease prevention, detection and response capacities.

CDC developed the proposed performance measures associated with this application based on the required activities of funded recipients, as outlined in the CK-24-0002 NOFO. ELC is an “umbrella” mechanism, and each of ELC’s 21 programs and projects align to a common set of objectives or overarching public health goals. Data elements defined by each project are outlined in the performance measures details guide associated with this application (see NCEZID_ELC_CK-24-0002_Performance Measures Detail Guide).

It is important to note that some ELC programs have submitted their own requests for performance measure data collection to OMB. These measures are intended to align with specific program objectives. Burden estimates from programs that have received OMB approval will not be included in this broader ELC application package and will be noted as Not Applicable (N/A). This approach is intended to prevent duplication of efforts and minimize the data collection burden on recipients.

ELC recognizes the recipient burden associated with collecting, maintaining, and reporting performance measure data to ELC. In preparation for CK-24-0002 project period (2023-2024), ELC worked with its CDC program partners to assess all measures with the goal of reducing recipient burden and ensuring all measures meet high standards (i.e., measures are meaningful, feasible, will be used by program, etc.). This assessment resulted in a significant reduction of approximately 40% of the number of measures and associated data elements that were a part of the CK-19-1902 cooperative agreement in the previous project period. Additionally, ELC is working to collaborate with other large CDC Cooperative Agreements to synchronize and share measures, and where possible, reduce the need for multiple performance measure reporting to different funders. For instance, ELC collects and shares several measures associated with Data Modernization activities with the PHIG CoAg.

To better understand recipient burden, over 10% of ELC recipients voluntarily shared how much time they spent collecting ELC performance measures (N=6), including time spent on preparation, quality assurance, analysis, and reporting to CDC. The information provided by the

recipients were used to estimate the overall reporting burden for this GenIC package. This GenIC package is being submitted in the second year of the five-year budget period. As such, our burden estimate accounts for time spent updating, reporting, and reviewing performance measures.

The ELC CK-24-0002 Performance Measures Detail Guide provides information on performance measures used by CDC partner programs to monitor progress and document impact of funding. Two types of performance measures are described in this guidance: ‘Active’ measures and ‘Passive’ indicators. ‘Active’ measures are performance measures that recipients will report on annually or biannually as indicated in the guidance. ‘Passive’ indicators are abstracted by CDC from other CDC data sources or external systems (e.g., National Outbreak Reporting System [NORS], National Notifiable Diseases Surveillance System [NNDSS]), alleviating the recipient’s reporting requirements. While ELC and its funding partners may use the ’Passive’ indicators to assess progress/performance, they do not need to be reported by recipients, as part of the annual performance measure reporting. The ‘Passive’ indicators are only listed in the guidance for recipient awareness since the ELC program and its funding partners also use these measures to understand the impact of their funded activities.

With only one exception, active measures will be collected once per year as noted in the table below. Data Modernization measures are collected twice (which is a 50% reduction from the quarterly collection in the previous CoAg) and shared with a variety of partners across CDC including PHIG and OPHDST, to inform how CDC provides time-sensitive technical assistance to recipients. Respondents will enter their performance measure information in a web-based Salesforce ELC Cooperative Agreement Management Platform (ELC CAMP), which uses built-in skip logic to show relevant questions for each program or project. The use of a web-based platform significantly streamlines recipients’ user experience, also helping to minimize reporting burden [NCEZID_ELC_CK-24-0002_CAMP Performance Measures Module].

CERTIFICATION:

I certify the following to be true:

1. The collection is non-controversial and does not raise issues of concern to other federal agencies.

2. Information gathered is meant primarily for program improvement and accountability; it is not intended to be used as the principal basis for policy decisions

Name:

Brittany Wright, MPH

ANNUALIZED BURDEN HOURS

This table calculates the total estimated burden per year for all recipients.

Type of Respondent	Form Name	No. of Respondents	No. of Responses per Respondent	Avg. Burden Per Response	Total Annualized Burden Hours
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Program A: Cross- cutting Epidemiology and Laboratory Capacity	65	1	2	130
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Program B: ELC Leadership, Management, and Administration1	N/A	N/A	N/A	N/A
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project C: Health Information System (HIS) Capacity	65	2	5	650
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project D: AMD: Advanced Molecular Detection	64	1	1	64
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide	65	1	4	260

	Project E: National Wastewater Surveillance System
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project F: Emerging Issues2	N/A	N/A	N/A	N/A
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Program G: Enteric, Foodborne, Waterborne, and Zoonotic Diseases: Surveillance, Detection, Response, Reporting, and Prevention	58	1	5	290
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Program H: Healthcare-associated Infections, Antimicrobial Resistance, and Antibiotic Stewardship3	N/A	N/A	N/A	N/A
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide	N/A	N/A	N/A	N/A

² There are no performance measures that recipients collect for Project F.

³ Performance measure burden estimates for this program have already been approved by OMB and are excluded from our calculation. See [OADPS/NCEZID] HAI/IR Programs (2023-2025) - OMB 0920-1282

	Program I: Antimicrobial Resistance Laboratory Network (AR Lab Network)4
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Program J: Enhanced Surveillance for Vaccine-Preventable Disease (VPD) and Respiratory Diseases	64	1	3	192
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Program K: Vector- borne Diseases and Tick-Associated Conditions:	60	1	5	300
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project L: Prion Surveillance	6	1	2	12
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project M: Mycotics: Detecting and Preventing Fungal Infections	40	1	1	40

⁴ Performance measure burden estimates for this program have already been approved by OMB and are excluded from our calculation. See [NCEZID] Public Health Laboratory Testing for Emerging Antibiotic Resistance and Fungal Threats - OMB 0920-1310

State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project N: Binational Border Infectious Disease Surveillance (BIDS)	4	1	2	8
State, Local, and Territorial Health Departments	Project O: Global Migration5	N/A	N/A	N/A	N/A
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project P: Parasitic Diseases Surveillance	7	1	1	7
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project Q: CARGOS: Combating Antimicrobial Resistant Gonorrhea and Other STIs	30	1	3	90
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project R: Rabies Surveillance and Laboratory Capacity	20	1	7/60	2
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project S: SET-NET: Surveillance for	15	1	13/60	3

⁵ Project O is not currently funded.

	Emerging Threats to Pregnant People and Infants Network
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project T: Human Papillomavirus Surveillance Among Men6	N/A	N/A	N/A	N/A
State, Local, and Territorial Health Departments	NCEZID_ELC_CK-24- 0002_Performance Measures Detail Guide Project U: HIV Centers for Cluster and Outbreak Response Enhancement (HIV C- CORE)7	N/A	N/A	N/A	N/A
Totals					2,048 Total Annual Burden Hours (Average of 32 hours/recipient)

To assist review, please answer the following questions:

ANNUALIZED BURDEN HOURS:

This table calculates the total estimated burden per year for all recipients.

TOTAL BURDEN HOURS FOR THIS GENIC:

This table specifies the calendar years in which information will be collected and calculates the total burden hours requested over the approved timeframe of the generic.

Data Collection Timeframe (List up to 3 Years)

No. Years Requested

Annualized Burden Hours

Total Burden Hours for this GENIC

⁶ There are no performance measures that recipients collect for Project T.

⁷ There are no performance measures that recipients collect for Project U.

2026, 2027, 2028

3

2,048

6,144

FEDERAL COST: The estimated annual cost to the Federal government is $46,200.00 per reporting cycle

Estimated # Hours it takes CDC Partner Programs/Projects to Review and Update ELC Performance measures	Upper GS-13 Hourly Rate	Number of CDC’s ELC Partner Programs with Performance measures	Estimated Annual Cost to Fed. Government
40 Hours	$70	188	$44,800
Estimated # Hours it takes CDC Partner Programs/Projects to Update the Measures Library in ELC CAMP	Upper GS-13 Hourly Rate	Number of ELC Partner Programs Responsible for Updating the ELC CAMP Performance measures Library	Estimated Annual Cost to Fed. Government
20 Hours	$70	1	$1,400
Total Federal Cost			$46,200

ADMINISTRATION OF THE INSTRUMENT:

1. How will you collect the information? (Check all that apply)

10. Web-based: NCEZID_ELC_CK24-0002_CAMP_Performance Measures Module [ ] Email

[ ] Postal Mail

[ ] Other, Explain:

Please make sure all instruments, instructions, and scripts are submitted with the request. Attachments

1. NCEZID_ELC_CK24-0002_Performance Measures Detail Guide

2. NCEZID_ELC_CK24-0002_CAMP_Performance Measures Module

3. NCEZID_ELC_CK24-0002_Performance Measures Recipient Notification

⁸ There are 21 CDC partner programs/projects that contribute to the ELC CoAg but only 18 have performance measures to review.