Non-Substantive Change Request Memo - 21JUL2025

Non-substantive Change Request – CDC 4.422 Form –

OMB Number: 0920-0006

We intend to amend one piece of instruction on our CDC 4.422 form, statements in support of applicant inadmissibility, which is part of the I-601 waiver process. This form allows us to receive information regarding how an I-601 applicant plans to receive treatment for their inadmissible mental health condition if granted admission to the U.S. Currently, the form instructs that individuals undergoing the I-601 waiver process print and mail it to our physical address here on Roybal campus. Several years ago, however, we transitioned our I-601 waiver review process to be fully digital in order to improve efficiency and to support the Paperwork Reduction Act (PRA). To align with this, we want to change the instructions on the 4.422 form to direct applicants to email a digital copy to a specified email address (waivers@cdc.gov), instead of physically mailing a paper copy to our mailing address.

The edits to the form itself include:

• removing our mailing address in two places (where Drew Posey’s signature blocks are)

• reducing the number of copies requested at the top of page 1

• adding the email address in two locations, on page 1 and page 2

There are no changes to the actual data collected, the intent of the form, or any other substantive content.