Attachment 4.3
Anniston Community Health Survey: Follow up Study and Dioxin Analyses
Reportable Reference Ranges for PCBs, Dioxins, and Other Chemicals
Table 1. Reference ranges for polychlorinated biphenyls (PCB)1 (ng/g lipid).
IUPAC No. |
Test Name |
NHANES Reference Range2 (Units) |
|
Polychlorinated biphenyls (PCBs) |
(ng/g lipid) |
PCB 28 |
2,4,4′-trichlorobiphenyl |
4.98 - 11.1 |
PCB 44 |
2,2’,3,5-tetrachlorobiphenyl |
2.00 - 5.44 |
PCB 49 |
2,2’,4,5’-tetrachlorobipheny |
1.33 - 3.36 |
PCB 52 |
2,2’,5,5’-tetrachlorobiphenyl |
2.70 - 7.15 |
PCB 66 |
2,3’,4,4’-tetrachlorobiphenyl |
1.40 - 4.20 |
PCB 74 |
2,4,4’,5-tetrachlorobiphenyl |
5.00 – 24.1 |
PCB 87 |
3,4,4',5-tetrachlorobiphenyl |
<LOD – 13.1 |
PCB 99 |
2,2’,3,4,5’-pentachlorobiphenyl |
0.90 - 2.60 |
PCB 101 |
2,2’,4,4’,5-pentachlorobiphenyl |
4.08 - 18.6 |
PCB 105 |
2,2’,4,5,5’-pentachlorobiphenyl† |
1.67 - 5.51 |
PCB 110 |
2,3,3’,4,4’-pentachlorobiphenyl |
1.15 - 6.82 |
PCB 118 |
2,3,3’,4’,6-pentachlorobiphenyl† |
1.20 - 4.18 |
PCB 128 |
3,3',4,4',5-pentachlorobiphenyl |
16.0 – 74.8 |
PCB 138-158 |
2,2’,3,3’,4,4’-hexachlorobiphenyl |
<LOD - 0.62 |
PCB 146 |
2,2’,3,4,4’,5’and 2,3,3’,4,4’,6-hexachlorobiphenyl |
17.6 – 77.4 |
PCB 149 |
2,2’,3,4’,5,5’-hexachlorobiphenyl |
2.60 - 12.7 |
PCB 151 |
2,2’,3,4’,5’,6-hexachlorobiphenyl |
0.60 - 1.89 |
PCB 153 |
2,2’,3,5,5’,6-hexachlorobiphenyl |
<LOD – 1.02 |
PCB 156 |
2,2’,4,4’,5,5’-hexachlorobiphenyl† |
24.2 - 101 |
PCB 157 |
2,3,3’,4,4’,5-hexachlorobiphenyl † |
4.10 – 16.8 |
PCB 167 |
2,3,3’,4,4’,5’-hexachlorobiphenyl † |
0.98 – 3.97 |
PCB 170 |
3,3',4,4',5,5'-hexachlorobiphenyl |
<LOD – 43.2 |
PCB 172 |
2,2’,3,3’,4,4’,5-heptachlorobiphenyl |
7.83 – 29.5 |
PCB 177 |
2,2’,3,3’,4,5,5’-heptachlorobiphenyl |
1.08 - 4.38 |
PCB 178 |
2,2’,3,3’,4’,5,6-heptachlorobiphenyl |
1.50 - 7.80 |
PCB 180 |
2,2’,3,3’,5,5’,6-heptachlorobiphenyl |
1.46 - 6.50 |
PCB 183 |
2,2’,3,4,4’,5,5’-heptachlorobiphenyl |
21.5 – 88.0 |
PCB 187 |
2,2’,3,4,4’,5’,6-heptachlorobiphenyl |
1.88 – 8.40 |
PCB 189 |
2,2’,3,4’,5,5’,6-heptachlorobiphenyl† |
5.71 – 25.9 |
PCB 194 |
2,3,3’,4,4’,5,5’-heptachlorobiphenyl |
<LOD – 1.50 |
PCB 195 |
2,2’,3,3’,4,4’,5,5’-octachlorobiphenyl |
4.95 - 20.1 |
PCB 196-203 |
2,2’,3,3’,4,4’,5,6-octachlorobiphenyl |
1.10 - 4.68 |
PCB 199 |
2,2’,3,3’,4,4’,5,6’and 2,2’,3,4,4’,5,5’,6-octachlorobiphenyl |
4.07 - 15.9 |
PCB 206 |
2,2’,3,3’,4,5,5’,6’-octachlorobiphenyl |
4.60 – 20.6 |
PCB 209 |
2,2’,3,3’,4,4’,5,5’,6’-nonachlorobiphenyl |
2.80 – 14.2 |
PCB 28 |
2,2’,3,3’,4,4’,5,5’,6,6’-decachlorobiphenyl |
1.40 – 12.3 |
1 Dioxin like coplanar PCB congeners results (PCBs 81, 126, and 169) are shown in Table 2.
2 CDC. 2009. 2003-2004 NHANES 50th to 95th percentiles among adults 20+ years old from the Fourth National Report on Human Exposure to Environmental Chemicals (http://www.cdc.gov/exposurereport/pdf/FourthReport.pdf).
<LOD – Below the limit of detection. †Mono-ortho substituted PCB congeners.
Table 2. Reference ranges for dioxins (PCDDs), dibenzofurans (PCDFs), coplanar PCBs, chlorinated pesticides and polybrominated diphenyl ethers (PBDEs).
Serial or IUPAC No. |
Test Name |
NHANES Reference Range1 (Units) |
|
Polychlorinated dibenzo-p-dioxins (PCDDs) |
(pg/g lipid) |
1 |
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) |
<LOD – 5.30 |
2 |
1,2,3,7,8-pentachlorodibenzo-p-dioxin (PeCDD) |
<LOD – 11.3 |
3 |
1,2,3,4,7,8-hexachlorodibenzo-p-dioxin (HxCDD) |
< LOD – < LOD |
4 |
1,2,3,6,7,8-hexachlorodibenzo-p-dioxin (HxCDD) |
23.8 – 70.8 |
5 |
1,2,3,7,8,9-hexachlorodibenzo-p-dioxin (HxCDD) |
< LOD – < LOD |
6 |
1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) |
27.3 – 95.0 |
7 |
1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin (OCDD) |
223 – 794 |
|
Polychlorinated dibenzo-p-furans (PCDFs) |
(pg/g lipid) |
1 |
2,3,7,8-tetrachlorodibenzofuran (TCDF) |
<LOD - <LOD |
2 |
1,2,3,7,8-pentachlorodibenzofuran (PeCDF) |
<LOD - <LOD |
3 |
2,3,4,7,8-pentachlorodibenzofuran (PeCDF) |
<LOD – 13.0 |
4 |
1,2,3,4,7,8-hexachlorodibenzofuran (HxCDF) |
<LOD – 9.50 |
5 |
1,2,3,6,7,8-hexachlorodibenzofuran (HxCDF) |
<LOD – 9.00 |
6 |
2,3,4,6,7,8-hexchlorodibenzofuran (HxCDF) |
<LOD - <LOD |
7 |
1,2,3,7,8,9-hexachlorodibenzofuran (HxCDF) |
<LOD - <LOD |
8 |
1,2,3,4,6,7,8-heptachlorodibenzofuran (HpCDF) |
<LOD – 18.0 |
9 |
1,2,3,4,7,8,9-heptachlorodibenzofuran (HpCDF) |
<LOD - <LOD |
10 |
1,2,3,4,6,7,8,9-octachlorodibenzofuran (OCDF) |
<LOD - <LOD |
|
Coplanar Polychlorinated Biphenyls (co-PCBs) |
(pg/g lipid) |
PCB 81 |
2,4,4’,5-tetrachlorobiphenyl |
0.006 – 0.17 |
PCB 126 |
2,3’,4,4’,5-pentachlorobiphenyl † |
5.56 – 34.3 |
PCB 169 |
2,3’,4,4’,5,5’-hexachlorobiphenyl † |
0.86 – 4.30 |
|
Chlorinated Pesticides |
(ng/g lipid) |
1 |
Hexachlorobenzene (HCB) |
15.1 – 29.0 |
2 |
β-Hexachlorocyclohexane (HCH) |
<LOD – 62.2 |
3 |
p,p'-Dichlorodiphenyltrichloroethane (DDT) |
<LOD – 20.7 |
4 |
p,p'-Dichlorodiphenyldichloroethene (DDE) |
233 – 1,990 |
5 |
Oxychlordane |
11.4 – 39.2 |
6 |
trans-Nonachlor |
17.3 – 74.7 |
7 |
Heptachlor epoxide |
<LOD – 20.6 |
8 |
Mirex |
<LOD – 15.4 |
9 |
Dieldrin |
<LOD – 19.5 |
|
Polybrominated diphenyl ethers (PBDEs) |
(ng/g lipid) |
BDE 17 |
2,2',4-tribromodiphenyl ether |
<LOD - <LOD |
BDE 28 |
2,4,4'-tribromodiphenyl ether |
1.10 – 8.20 |
BDE 47 |
2,2',4,4'-tetrabromodiphenyl ether |
18.0 – 163 |
BDE 66 |
2,3',4,4'-tetrabromodiphenyl ether |
<LOD – 1.30 |
BDE 85 |
2,2',3,4,4'-pentabromodiphenyl ether |
<LOD – 4.10 |
BDE 99 |
2,2',4,4',5-pentabromodiphenyl ether |
<LOD – 41.6 |
BDE 100 |
2,2',4,4',6-pentabromodiphenyl ether |
3.30 – 36.6 |
BDE 153 |
2,2',4,4',5,5'-hexabromodiphenyl ether |
4.40 – 73.3 |
BDE 154 |
2,2',4,4',5,6'-hexabromodiphenyl ether |
<LOD – 4.20 |
BDE 183 |
2,2',3,4,4',5',6-heptabromodiphenyl ether |
<LOD - <LOD |
1 CDC. 2009. 2003-2004 NHANES 50th to 95th percentiles among adults 20+ years old from the Fourth National Report on Human Exposure to Environmental Chemicals (http://www.cdc.gov/exposurereport/pdf/FourthReport.pdf).
<LOD – Below the limit of detection.
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