Attach 13A-13D Phase III Buccal Pre-Contact Letters

ATTACHMENT 13

Iowa Phase III Buccal Pre-Contact Letters and
Collection Kit Cover Letters
13A. Phase III Buccal Cell Pre-Contact Letter for Iowa
Respondents with Prostate Cancer
13B. Phase III Buccal Cell Contact Cover Letter with Kit for Iowa
Respondents with Prostate Cancer
13C. Phase III Buccal Cell Pre-Contact Letter for Iowa
Respondents with NHL
13D. Phase III Buccal Cell Contact Cover Letter with Kit for Iowa
Respondents

Attachment 13A: Phase III Buccal Cell Pre-Contact Letter for Iowa Respondents with Prostate
Cancer

Agricultural Health Study
Iowa Field Station

THE UNIVERSITY OF IOWA • 100 OAKDALE CAMPUS • N251 OH • IOWA CITY, IA 52242-5000 • 1.800.217.1954

www.aghealth.org
Executive Committee
Michael C. R. Alavanja, Dr. P.H.
Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8000
Rockville, MD 20852
Tel 301.435.4720
Aaron Blair, Ph.D.
Assistant Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8118
Rockville, MD 20852
Tel 301.496.9094
Jane A. Hoppin, Sc.D.
Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.7622
Dale P. Sandler, Ph.D.
Chief, Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.4668
Kent Thomas
Team Leader, Agricultural Health
Study Pesticide Exposure Study
National Exposure Research
Laboratory
U.S. Environmental Protection Agency
Mail Drop E205-04
Research Triangle Park, NC 27711
Tel 919.541.7939

Area Directors
Charles Knott, M.P.A.
North Carolina Director
Battelle
Centers for Public Health
Research & Evaluation
100 Capitola Drive
Durham, NC 27713
Tel 919.544.3717
Charles F. Lynch, M.D., Ph.D.
Iowa Director
University of Iowa
Department of Epidemiology
C21-L GH
Iowa City, IA 52242
Tel 319.384.5006
Marsha Dunn, M.P.H.
Coordinating Center Director
Westat
1650 Research Blvd.
Rockville, MD 20850
Tel 301.738.3557

[date]
To:

Agricultural Health Study Participant

From: Charles Lynch, M.D., Ph.D.
Director, Iowa Field Station
Thank you for continuing to participate in the Agricultural Health Study. You
are an essential member of this study, which is designed to learn about how
occupation and environmental factors affect an individual’s health. Thanks to
your participation, this now is the largest one of its kind in the United States.
The main goal of this study is to look at pesticide exposures and chronic health
conditions. Now that we are learning more about possible links between
prostate cancer and pesticide use, we would like you to consider participating in
an additional research effort. You are one of about 1,000 members of the
Agricultural Health Study who have been selected to be contacted about this
study. Because you have already contributed a tremendous amount of
information about your pesticide exposure in previous interviews and
questionnaires, this new study will have a head-start in understanding the
relationship of prostate cancer to these exposures. The study will include people
who have not been diagnosed with prostate cancer as well as people who have
had this disease. The experiences of these two groups will then be compared.
We would like you to collect a sample of loose cells from your mouth. You may

have done so for us in a previous effort, but this sample will be reserved
specifically for later laboratory analysis that will involve genetic testing. Your
participation will take only a few minutes and will provide very important
information for the study.
We will be calling you within a few days to explain the procedure and answer
any questions you may have. In the meantime, if you have any questions, please
call us at 1-800-217-1954. We will be glad to assist you.
We truly value your continued participation in this landmark study of
agricultural workers and their families. Because you have already provided us
with valuable information no other person can take your place.
Thank you once again for your time and support.

Attachment 13B:
Phase III Buccal Cell Contact Letter with Kit for Iowa Respondents with Prostate Cancer

Agricultural Health Study
Iowa Field Station

THE UNIVERSITY OF IOWA • 100 OAKDALE CAMPUS • N251 OH • IOWA CITY, IA 52242-5000 • 1.800.217.1954

www.aghealth.org

[date]

Executive Committee
Michael C. R. Alavanja, Dr. P.H.
Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8000
Rockville, MD 20852
Tel 301.435.4720
Aaron Blair, Ph.D.
Assistant Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8118
Rockville, MD 20852
Tel 301.496.9094
Jane A. Hoppin, Sc.D.
Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.7622
Dale P. Sandler, Ph.D.
Chief, Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.4668
Kent Thomas
Team Leader, Agricultural Health
Study Pesticide Exposure Study
National Exposure Research
Laboratory
U.S. Environmental Protection Agency
Mail Drop E205-04
Research Triangle Park, NC 27711
Tel 919.541.7939

Area Directors
Charles Knott, M.P.A.
North Carolina Director
Battelle
Centers for Public Health
Research & Evaluation
100 Capitola Drive
Durham, NC 27713
Tel 919.544.3717
Charles F. Lynch, M.D., Ph.D.
Iowa Director
University of Iowa
Department of Epidemiology
C21-L GH
Iowa City, IA 52242
Tel 319.384.5006
Marsha Dunn, M.P.H.
Coordinating Center Director
Westat
1650 Research Blvd.
Rockville, MD 20850
Tel 301.738.3557

To:

Agricultural Health Study Participant

From: Charles Lynch, M.D., Ph.D.
Director, Iowa Field Station
Thank you for your past participation in the Agricultural Health Study.
You are one of nearly 59,000 people (mostly farmers and their spouses) in Iowa
who enrolled in this study between 1993 and 1997. The study is designed to
learn about how occupation and environmental factors affect an individual’s
health. Thanks to your participation, this now is the largest study of its kind in
the United States.
The main goal of this study is to look at pesticide exposures and chronic
health conditions. Now that we are learning more about possible links between
prostate cancer and pesticide use, we would like you to consider participating in
an additional research effort. You are one of about 1,000 members of the
Agricultural Health Study who have been selected to be contacted about this
study. Because you have already contributed a tremendous amount of
information about your pesticide exposure in previous interviews and
questionnaires, this new study will have a head-start in understanding the
relationship of prostate cancer to these exposures. The study will include people
who have not been diagnosed with prostate cancer as well as people who have
had this disease. The experiences of these two groups will then be compared.
We would like you to collect a sample of loose cells from your mouth. You
may have done so for us in a previous effort, but this sample will be reserved
specifically for later laboratory analysis that will involve genetic testing.
Simply swish the mouthwash in your mouth and then expel it into the
accompanying container (see the enclosed DIRECTIONS FOR
MOUTHWASH). In this package you will find everything you need, including
consent forms. We also enclosed a $5 check for your time and effort in
collecting and mailing the sample. Once you collect this sample, please return it
as soon as possible in the enclosed padded envelope. Your participating will
take only a few minutes and will provide very important information for the
study.
If you have questions, please call us at 1-800-217-1954. We will be glad
to assist you. We truly value your continued participation in this landmark study
of agricultural workers and their families. Because you have already provided
us with valuable information no other person can take your place.
Thank you once again for your time and support.

Attachment 13C:
Phase III Buccal Cell Pre-Contact Letter for Iowa Respondents with NHL

Agricultural Health Study
Iowa Field Station

THE UNIVERSITY OF IOWA • 100 OAKDALE CAMPUS • N251 OH • IOWA CITY, IA 52242-5000 • 1.800.217.1954

www.aghealth.org
Executive Committee
Michael C. R. Alavanja, Dr. P.H.
Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8000
Rockville, MD 20852
Tel 301.435.4720
Aaron Blair, Ph.D.
Assistant Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8118
Rockville, MD 20852
Tel 301.496.9094
Jane A. Hoppin, Sc.D.
Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.7622
Dale P. Sandler, Ph.D.
Chief, Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.4668
Kent Thomas
Team Leader, Agricultural Health
Study Pesticide Exposure Study
National Exposure Research
Laboratory
U.S. Environmental Protection Agency
Mail Drop E205-04
Research Triangle Park, NC 27711
Tel 919.541.7939

[date]
To:

Agricultural Health Study Participant

From: Charles Lynch, M.D., Ph.D.
Director, Iowa Field Station
Thank you for continuing to participate in the Agricultural Health Study. You
are an essential member of this study, which is designed to learn about how
occupation and environmental factors affect an individual’s health. Thanks to
your participation, this now is the largest one of its kind in the United States.
The main goal of this study is to look at pesticide exposures and chronic health
conditions. Now that we are learning more about possible links between nonHodgkin lymphoma and pesticide use, we would like you to consider
participating in an additional research effort. You are one of about 500 members
of the Agricultural Health Study who have been selected to be contacted about
this study. Because you have already contributed a tremendous amount of
information about your pesticide exposure in previous interviews and
questionnaires, this new study will have a head-start in understanding the
relationship of non-Hodgkin lymphoma to these exposures. The study will
include people who have not been diagnosed with non-Hodgkin lymphoma as
well as people who have had this disease. The experiences of these two groups
will then be compared.
We would like you to collect a sample of loose cells from your mouth. You may

have done so for us in a previous effort, but this sample will be reserved
specifically for later laboratory analysis that will involve genetic testing. Your
participation will take only a few minutes and will provide very important
information for the study.

Area Directors
Charles Knott, M.P.A.
North Carolina Director
Battelle
Centers for Public Health
Research & Evaluation
100 Capitola Drive
Durham, NC 27713
Tel 919.544.3717
Charles F. Lynch, M.D., Ph.D.
Iowa Director
University of Iowa
Department of Epidemiology
C21-L GH
Iowa City, IA 52242
Tel 319.384.5006
Marsha Dunn, M.P.H.
Coordinating Center Director
Westat
1650 Research Blvd.
Rockville, MD 20850
Tel 301.738.3557

We will be calling you within a few days to explain the procedure and answer
any questions you may have. In the meantime, if you have any questions, please
call us at 1-800-217-1954. We will be glad to assist you.
We truly value your continued participation in this landmark study of
agricultural workers and their families. Because you have already provided us
with valuable information no other person can take your place.
Thank you once again for your time and support.

Attachment 13D:
Phase III Buccal Cell Contact Letter with Kit for Iowa Respondents with NHL

Agricultural Health Study
Iowa Field Station

THE UNIVERSITY OF IOWA • 100 OAKDALE CAMPUS • N251 OH • IOWA CITY, IA 52242-5000 • 1.800.217.1954

www.aghealth.org

[date]

Executive Committee
Michael C. R. Alavanja, Dr. P.H.
Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8000
Rockville, MD 20852
Tel 301.435.4720
Aaron Blair, Ph.D.
Assistant Project Officer
National Cancer Institute
National Institutes of Health
U.S. Department of Health and
Human Services
Executive Plaza South, RM 8118
Rockville, MD 20852
Tel 301.496.9094
Jane A. Hoppin, Sc.D.
Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.7622
Dale P. Sandler, Ph.D.
Chief, Epidemiology Branch
National Institute of Environmental
Health Sciences
National Institutes of Health
U.S. Department of Health and
Human Services
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, NC 27709
Tel 919.541.4668
Kent Thomas
Team Leader, Agricultural Health
Study Pesticide Exposure Study
National Exposure Research
Laboratory
U.S. Environmental Protection Agency
Mail Drop E205-04
Research Triangle Park, NC 27711
Tel 919.541.7939

Area Directors
Charles Knott, M.P.A.
North Carolina Director
Battelle
Centers for Public Health
Research & Evaluation
100 Capitola Drive
Durham, NC 27713
Tel 919.544.3717
Charles F. Lynch, M.D., Ph.D.
Iowa Director
University of Iowa
Department of Epidemiology
C21-L GH
Iowa City, IA 52242
Tel 319.384.5006
Marsha Dunn, M.P.H.
Coordinating Center Director
Westat
1650 Research Blvd.
Rockville, MD 20850
Tel 301.738.3557

To:

Agricultural Health Study Participant

From: Charles Lynch, M.D., Ph.D.
Director, Iowa Field Station
Thank you for your past participation in the Agricultural Health Study.
You are one of nearly 59,000 people (mostly farmers and their spouses) in Iowa
who enrolled in this study between 1993 and 1997. The study is designed to
learn about how occupation and environmental factors affect an individual’s
health. Thanks to your participation, this now is the largest study of its kind in
the United States.
The main goal of this study is to look at pesticide exposures and chronic
health conditions. Now that we are learning more about possible links between
non-Hodgkin lymphoma and pesticide use, we would like you to consider
participating in an additional research effort. You are one of about 500 members
of the Agricultural Health Study who have been selected to be contacted about
this study. Because you have already contributed a tremendous amount of
information about your pesticide exposure in previous interviews and
questionnaires, this new study will have a head-start in understanding the
relationship of non-Hodgkin lymphoma to these exposures. The study will
include people who have not been diagnosed with non-Hodgkin lymphoma as
well as people who have had this disease. The experiences of these two groups
will then be compared.
We would like you to collect a sample of loose cells from your mouth. You
may have done so for us in a previous effort, but this sample will be reserved
specifically for later laboratory analysis that will involve genetic testing.
Simply swish the mouthwash in your mouth and then expel it into the
accompanying container (see the enclosed DIRECTIONS FOR
MOUTHWASH). In this package you will find everything you need, including
consent forms. We also enclosed a $5 check for your time and effort in
collecting and mailing the sample. Once you collect this sample, please return it
as soon as possible in the enclosed padded envelope. Your participating will
take only a few minutes and will provide very important information for the
study.
If you have questions, please call us at 1-800-217-1954. We will be glad
to assist you. We truly value your continued participation in this landmark study
of agricultural workers and their families. Because you have already provided
us with valuable information no other person can take your place.
Thank you once again for your time and support.