Attach 12B_Westat 2007 IRB_7874-Annual

TO: Marsha Dunn August 22, 2007

Project Director

FROM: Thomas W. McKenna

Chairman, Institutional Review Board

SUBJECT: IRB Annual Review and Approval

Agricultural Health Study

Contract N02-CP-45501

Project 7874

FWA 5551

_____________________________________________________________________________________

On August 17, 2007, the Westat Institutional Review Board conducted its annual review of the following: Agricultural Health Study, Contract N02-CP-45501, Project 7874. Pursuant to 45 CFR pt 46.109(e), the IRB conducts continuing reviews of previously approved research on an annual basis.

In accordance with 45 CFR pt 46, the Board approved the continuation of this study. The next annual review will be due on or before August 17, 2008. In the interim, you are responsible for notifying the Office of Research Administration as soon as possible if there are any injuries to the subjects, problems with the study, or changes to study design that relate to human subjects.

cc: Institutional Review Board

Jeanne Rosenthal