Comment in response to 60-day notice

From: Marcia Greenblum [mailto:mgreenblum@enc-online.org]
Sent: Tuesday, November 20, 2007 2:53 PM
To: Sorlie, Paul (NIH/NHLBI) [E]
Subject: dietary cholesterol intake from eggs

Hello Dr. Sorlie:

          I understand that the NHLBI is asking for comments regarding the Framingham study's review of determinants of cardiovascular disease. As you know, egg intake has been associated with cardiovascular in the US for some time although recent research into LDL:HDL ratios, vascular inflammation and saturated fat/cholesterol intake has shown no association.

          I'm wondering if the proposed new look at the Framingham data will include a look into dietary cholesterol intake related to heart disease risk?  Several countries around the world have dropped their dietary cholesterol restrictions due to lack of evidence of risk. If you think dietary cholesterol intake will be included in this research agenda, I will gladly file formal comments.

Thank you,

Marcia Greenblum

Marcia Greenblum MS, RD

Director, Nutrition and Food Safety Education

Egg Nutrition Center

1900 L Street NW, Suite 725

Washington, DC 20036

Phone: (202) 833-8850

Fax: (202) 463-0102

Email: mgreenblum@enc-online.org

From: Sorlie, Paul (NIH/NHLBI) [E]
Sent: Thursday, December 06, 2007 5:49 PM
To: 'Marcia Greenblum'
Subject: RE: dietary cholesterol intake from eggs

Marcia Greenblum:

 

The proposal for new data collection from the Framingham Study will include a food frequency questionnaire.  This questionnaire has been used previously in Framingham.  By including it there will be ample opportunity to investigate the relationship between dietary cholesterol intake (as well as can be estimated with a food frequency questionnaire) and the extensive collection of phenotypic data available in the Framingham Heart Study.

 

Thank you, and I hope that this answers your question.

 

Paul Sorlie, Ph.D.

Project Officer, Framingham Heart Study

NHLBI, NIH